Immune Adherence of Leucocytes and Fibroblasts Derived from Skin, Sensitized by Cytotoxic Leucocyte Iso-Antibodies and Complement, to the Surface of Indicator Cells

Summary Evidence was found that human lymphocytes and fibroblasts derived from human skin, sensitized by cytotoxic leucocyte iso-antibodies and complement adhere to the surface of indicator cells. The reaction mechanism showed the characteristics of the immune adherence (I.A.) phenomenon. Experiments made clear that in the I.A. assay the same antibody is detected as in the cytotoxic antibody test, based on dye exclusion. The sensitivity of the I.A. assay was shown to surpass slightly that of the cytotoxic antibody test.