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Lecithin: Cholesterol Acyltransferase Activity in the Plasma of Rats Fed Sucrose or Starch
- Source :
- Annals of Nutrition and Metabolism. 13:172-177
- Publication Year :
- 1971
- Publisher :
- S. Karger AG, 1971.
-
Abstract
- The substitution of sucrose for starch in the diet of the rat promotes a rise in the plasma cholesterol concentration which is largely confined to the esterified fraction. There is a concomitant rise in the activity of the enzyme lecithin:cholesterol acyltransferase which catalyses the esterification of free cholesterol in the plasma. This enzyme displays a marked specificity towards the cholesterol carried in the high-density lipoproteins. It is concluded that the increase in the capacity of the plasma to esterify cholesterol occurs in response to the increased throughput of cholesterol in the plasma which results from feeding a high-sucrose diet.
- Subjects :
- Male
Sucrose
Starch
Lecithin:cholesterol acyltransferase activity
Lipoproteins
Sterol O-acyltransferase
Medicine (miscellaneous)
chemistry.chemical_compound
Plasma cholesterol
Blood plasma
Dietary Carbohydrates
Animals
Food science
Nutrition and Dietetics
Cholesterol
Esters
Stimulation, Chemical
Rats
Liver
chemistry
Biochemistry
Acyltransferase
Phosphatidylcholines
lipids (amino acids, peptides, and proteins)
Acyltransferases
Subjects
Details
- ISSN :
- 14219697 and 02506807
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- Annals of Nutrition and Metabolism
- Accession number :
- edsair.doi.dedup.....59a0b07fa627927d4cf17e0bb0269d05