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The sense of place in the immune system
- Source :
- Nature immunology. 7(4)
- Publication Year :
- 2006
-
Abstract
- This series of reviews examines the effect of differing tissue environments on the activity and functional capacity of cells in the immune system. From their origins as hematopoietic stem cells, throughout their development and as mature cells, cells of the immune system find themselves in distinct and highly specialized niches, and contact with antigen or inflammatory signals changes their phenotype, activity and trafficking. Two-photon microscopy has provided the first direct observations of living cells and their activation choreography in the tissue environment and will no doubt continue to provide greater understanding of cellular dynamics and immune function.
- Subjects :
- Innate immune system
Immunology
Antigen presentation
Lymphokine
Thymus Gland
Biology
biochemical phenomena, metabolism, and nutrition
Acquired immune system
Hematopoietic Stem Cells
Article
Cell biology
B-1 cell
Immune system
Cell Movement
Immune System
Lymph node stromal cell
Immunology and Allergy
bacteria
Animals
Humans
Cell Lineage
Lymph Nodes
Lymphocytes
Adult stem cell
Subjects
Details
- ISSN :
- 15292908
- Volume :
- 7
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Nature immunology
- Accession number :
- edsair.doi.dedup.....59682104dcd3235ce10bb78247bd9c6f