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Down-regulation of ANT2 and HSP90 mRNA levels by siRNA from Targeting Adenine Nucleotide Translocase-2 (ANT2) to Overcome Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Non–Small Cell Lung Cancer

Authors :
Chul Woo Kim
Yoon Kyung Jeon
Tae Min Kim
Bhumsuk Keam
Soo Jeong Nam
Yong-goo Kim
Ji-Young Jang
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

H1975 cells were transfected with ANT siRNA, HSP90 siRNA or scramble (sc) siRNA. At 24 hours of transfection, expression levels of ANT2 and HSP90 were measured using qRT-PCR and the suppressive efficiency of siRNA was presented by relative expression levels (2-ddCt) of ANT2 and HSP90 compared with those of cells transfected with sc siRNA.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....595e8cfbcef49bdf10d88262e263b921