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Effects of Dietary Pb on Accumulation, Histopathology, and Digestive Enzyme Activities in the Digestive System of Tilapia (Oreochromis niloticus)
- Source :
- Biological Trace Element Research. 127:124-131
- Publication Year :
- 2008
- Publisher :
- Springer Science and Business Media LLC, 2008.
-
Abstract
- With the increasing occurrence of dietary lead (Pb) contamination in aquatic environment, threat of the dietary Pb toxicity to aquatic organisms attracted more attention. In this study, after being exposed to dietary Pb at concentrations of 0, 100, 400, and 800-μg/g dry weight for 60 days, the groups of tilapia (Oreochromis niloticus) were sacrificed and sampled to analyze the effects of dietary Pb on accumulation, histopathology, and digestive enzyme activities in tissues of the digestive system. The results showed that the Pb accumulation in tissues increased with the dietary Pb concentrations. Moreover, Pb accumulated in sampled tissues in the following order: intestine > stomach > liver. By observation of liver histological sections in optical microscope, lesions could be detected in the Pb-contaminated groups. It was also demonstrated that the inhibitory effect of dietary Pb on digestive enzyme activities was dietary Pb concentration dependent. Different degrees of inhibition of enzyme activities were exhibited in sampled tissues. It was indicated that digestive enzyme activities in the digestive system might be considered as the potential biomarkers of dietary Pb contamination in tilapia.
- Subjects :
- Male
food.ingredient
Endocrinology, Diabetes and Metabolism
Clinical Biochemistry
Biochemistry
Inorganic Chemistry
Toxicology
Random Allocation
food
Dry weight
medicine
Animals
Trypsin
Food science
Intestinal Mucosa
biology
Stomach
Biochemistry (medical)
Aquatic animal
Tilapia
Lipase
General Medicine
biology.organism_classification
Enzyme assay
Diet
Intestines
Oreochromis
medicine.anatomical_structure
Lead
Liver
Gastric Mucosa
Amylases
Toxicity
Digestive enzyme
biology.protein
Trypsin Inhibitors
Digestive System
Subjects
Details
- ISSN :
- 15590720 and 01634984
- Volume :
- 127
- Database :
- OpenAIRE
- Journal :
- Biological Trace Element Research
- Accession number :
- edsair.doi.dedup.....592aef96e070b21364408286ee848175