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SARS-CoV-2 and the cardiovascular system
- Source :
- Clinica Chimica Acta; International Journal of Clinical Chemistry, Clinica Chimica Acta
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- Highlights • Severe acute respiratory syndrome CoV-2 can interacts with cardiovascular system. • COVID-19 potentiates existing cardiovascular diseases. • Risk factor for cardiovascular disease are common in COVID-19. • A number of patients with COVID-19 manifest an increase in cardiac biomarkers release. • Cardiovascular complications were independently reported with COVID-19 infections.<br />The coronavirus disease COVID-19 is a public health emergency caused by a novel coronavirus named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 infection uses the angiotensin-converting enzyme 2 (ACE2) receptor, and typically spreads through the respiratory tract. Invading viruses can elicit an exaggerated host immune response, frequently leading to a cytokine storm that may be fueling some COVID-19 death. This response contributes to multi-organ dysfunction. Accumulating data points to an increased cardiovascular disease morbidity, and mortality in COVID-19 patients. This brief review explores potential available evidence regarding the association between COVID-19, and cardiovascular complications.
- Subjects :
- 0301 basic medicine
viruses
Pneumonia, Viral
Clinical Biochemistry
ACE2
severe acute respiratory syndrome
Disease
Peptidyl-Dipeptidase A
medicine.disease_cause
Cardiovascular System
Biochemistry
Article
Renin-Angiotensin System
Betacoronavirus
03 medical and health sciences
0302 clinical medicine
Immune system
Pandemic
Humans
Medicine
myocardial injury
Molecular Targeted Therapy
Respiratory system
Pandemics
Coronavirus
Biochemistry, medical
biology
SARS-CoV-2
troponin
business.industry
Biochemistry (medical)
COVID-19
General Medicine
biology.organism_classification
medicine.disease
030104 developmental biology
medicine.anatomical_structure
030220 oncology & carcinogenesis
Immunology
Angiotensin-Converting Enzyme 2
Coronavirus Infections
business
Cytokine storm
Respiratory tract
Subjects
Details
- ISSN :
- 00098981
- Volume :
- 510
- Database :
- OpenAIRE
- Journal :
- Clinica Chimica Acta
- Accession number :
- edsair.doi.dedup.....5929af8178a6afe3f42335cf392928e9