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Assessment of serum symmetric dimethylarginine and creatinine concentrations in cats with urethral obstruction
- Source :
- Journal of feline medicine and surgery. 24(10)
- Publication Year :
- 2021
-
Abstract
- Objectives The aims of this study were to evaluate serum symmetric dimethylarginine (SDMA) and creatinine concentrations in cats with urethral obstruction pre- and post-decompression of the obstruction, and to determine if pre-decompression values were predictive of post-decompression renal function, as measured by SDMA and creatinine. Methods This was a prospective observational study. Twenty-five client-owned cats with urethral obstruction were hospitalized for decompression of the obstruction. Serum SDMA and creatinine were prospectively assessed at presentation, 24 h post-decompression and 5–20 days post-decompression. Urinalysis and culture were assessed at presentation and at the final follow-up. Exclusion criteria included positive urine culture, reobstruction or failure to obtain required samples. Results Mean SDMA concentration dropped by 41.8% from an initial pre-decompression concentration of 17.6 µg/dl to 10.3 µg/dl 24 h post-decompression ( P Conclusions and relevance Both SDMA and creatinine decreased significantly after urethral catheterization, suggesting that renal function post-decompression cannot be predicted by the pre-decompression concentrations of these values.
Details
- ISSN :
- 15322750
- Volume :
- 24
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Journal of feline medicine and surgery
- Accession number :
- edsair.doi.dedup.....59207f5ee6a8db282d82b61bb7d3dc8d