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Re-pigmentation of hair after prolonged cholinesterase inhibitor therapy in a Chinese population
- Source :
- The Australasian journal of dermatologyReferences. 61(4)
- Publication Year :
- 2020
-
Abstract
- Eighty consecutive Chinese patients diagnosed with Alzheimer disease were assessed for darkening of grey hair. Of the 62 eligible patients (mean age = 79.3 ± 7.9 years; male: female = 1:1.48), 24/62 (38.7%, 95%CI: 26.6 – 51.9) reported hair darkening after prolonged usage of cholinesterase inhibitor for at least 6 months. Of the 24 patients with hair darkening, 17 (70.9%) experienced hair darkening in the occipital region, 3 (12.5%) in the parietal region, 2 (8.3%) patients in the frontal region and 2 (8.3%) patients experienced hair darkening in multiple regions. Analysis of melanin concentration showed no significant difference between darkened hair of patients after prolonged drug use and the dark hair of controls (P = 0.381).
- Subjects :
- Male
Physiology
Dermatology
Melanin
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
Asian People
Alzheimer Disease
Medicine
Humans
Parietal region
Frontal region
Hair Color
Cholinesterase
Aged
Chinese population
integumentary system
biology
business.industry
fungi
Significant difference
Mean age
medicine.disease
030220 oncology & carcinogenesis
biology.protein
Female
sense organs
Cholinesterase Inhibitors
Alzheimer's disease
business
Subjects
Details
- ISSN :
- 14400960
- Volume :
- 61
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- The Australasian journal of dermatologyReferences
- Accession number :
- edsair.doi.dedup.....58f488a93f179dc4f72dec0b280983b4