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Supplementary Figures 1-7, Tables 1-4 from Analysis of Fcγ Receptor IIIa and IIa Polymorphisms: Lack of Correlation with Outcome in Trastuzumab-Treated Breast Cancer Patients

Authors :
John M. Timmerman
Dennis J. Slamon
Omkar Marathe
Valerie Bee
Miguel Martin
Wolfgang Eiermann
Tadeusz Pienkowski
Adam Brufsky
Carla Falkson
John Crown
Vicente Valero
Nicholas J. Robert
Mark X. Sliwkowski
Sambasivarao Damaraju
Adrian Driga
John Mackey
Marc Buyse
Ying Zhao
Somasekar Seshagiri
Jeremy Stinson
Emmanuel Quinaux
Howard M. Stern
David J. Betting
Sara A. Hurvitz
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

PDF file - 507K, Supplemental Table 1A: PCR and Sanger Sequencing Primers Supplemental Table 1B: PCR and Sequenom Genotyping Primers Supplemental Figure 1. Kaplan-Meier estimates of disease free survival for BCIRG 006 study, entire population, third planned analysis. (N=3222) Supplemental Table 2. Patient Characteristics: Genotyped vs. Non-genotyped Supplemental Figure 2. Kaplan-Meier estimates of disease free survival in subset of patients enrolled in BCIRG006 (third planned analysis) who were genotyped for this study (N=1,286) Supplemental Figure 3. Kaplan-Meier estimates of disease free survival in subset of patients enrolled in BCIRG006 (third planned analysis) who were genotyped for this study with stratification for major prognostic factors Supplemental Table 3. Patients Characteristics by Genotype (Advanced Disease Cohort) Supplemental Table 4. Genotype and Allele Frequencies of the FCGR2A and FCGR3A Polymorphisms Supplemental Figure 4. Kaplan-Meier estimates of disease free survival in trastuzumab treated patients within the adjuvant cohort according to FcGammaR polymorphisms, broken down by treatment arm Supplemental Figure 5. Kaplan-Meier estimates of disease free survival in patients treated with chemotherapy alone (no trastuzumab) in the adjuvant cohort according to FcGammaR polymorphisms, broken down by treatment arm. Supplemental Figure 6. Kaplan-Meier estimates of overall survival (OS) in trastuzumab treated patients within the adjuvant cohort according to FcGammaR polymorphisms. Supplemental Figure 7. Kaplan-Meier estimates of progression free survival (PFS) in trastuzumab treated patients within the advanced disease cohort according to FcGammaR polymorphisms.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....58f2b4ecd166fdf6937eb5cfca203e4a
Full Text :
https://doi.org/10.1158/1078-0432.22443573