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Angiographic and structural imaging using high axial resolution fiber-based visible-light OCT
- Publication Year :
- 2017
- Publisher :
- Optical Society of America, 2017.
-
Abstract
- Optical coherence tomography using visible-light sources can increase the axial resolution without the need for broader spectral bandwidth. Here, a high-resolution, fiber-based, visible-light optical coherence tomography system is built and used to image normal retina in rats and blood vessels in chicken embryo. In the rat retina, accurate segmentation of retinal layer boundaries and quantification of layer thicknesses are accomplished. Furthermore, three distinct capillary plexuses in the retina and the choriocapillaris are identified and the characteristic pattern of the nerve fiber layer thickness in rats is revealed. In the chicken embryo model, the microvascular network and a venous bifurcation are examined and the ability to identify and segment large vessel walls is demonstrated.
- Subjects :
- Materials science
genetic structures
Capillary action
Nerve fiber layer
Image processing
01 natural sciences
Article
010309 optics
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Optics
Optical coherence tomography
0103 physical sciences
medicine
Fiber
Retina
medicine.diagnostic_test
business.industry
Retinal
Atomic and Molecular Physics, and Optics
medicine.anatomical_structure
chemistry
030221 ophthalmology & optometry
sense organs
business
Biotechnology
Photonic-crystal fiber
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....58b2643e61623f8fe3aae0a6c81b6def