Lagos bat virus transmission in an Eidolon helvum bat colony, Ghana

Authors :: Tabea Binger
Samual K. Oppong
Melina Fischer
Dirk Höper
Martin Beer
Yaw Adu-Sarkodie
Juliane Schatz
Conrad M. Freuling
Bernd Hoffmann
Thomas Müller
Thomas C. Mettenleiter
Christian Drosten
Dennis Hanke
Source :: Virus Research. 210:42-45
Publication Year :: 2015
Publisher :: Elsevier BV, 2015.
Abstract: A brain sample of a straw-coloured fruit bat (Eidolon helvum) from Ghana without evident signs of disease tested positive by generic Lyssavirus RT-PCR and direct antigen staining. Sequence analysis confirmed the presence of a Lagos bat virus belonging to phylogenetic lineage A. Virus neutralization tests using the isolate with sera from the same group of bats yielded neutralizing antibodies in 74% of 567 animals. No cross-neutralization was observed against a different Lagos bat virus (lineage B).

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