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Glucosinolate-Derived Isothiocyanates Inhibit Arabidopsis Growth and the Potency Depends on Their Side Chain Structure
- Source :
- International Journal of Molecular Sciences; Volume 18; Issue 11; Pages: 2372, International Journal of Molecular Sciences, International Journal of Molecular Sciences, Vol 18, Iss 11, p 2372 (2017)
- Publication Year :
- 2017
- Publisher :
- Multidisciplinary Digital Publishing Institute, 2017.
-
Abstract
- Isothiocyanates (ITCs), the biologically important glucosinolate breakdown products, can present health-promoting effects, play an important role in plant defense and affect plant cellular mechanisms. Here, we evaluated the biological effects of ITCs on Arabidopsis thaliana by assessing growth parameters after long-term exposure to low concentrations of aliphatic and aromatic ITCs, ranging from 1 to 1000 µM. Treatment with the aliphatic allylisothiocyanate (allyl-ITC) led to a significant reduction of root length and fresh weight in a dose-dependent manner and affected the formation of lateral roots. To assess the importance of a hormonal crosstalk in the allyl-ITC-mediated growth reduction, the response of auxin and ethylene mutants was investigated, but our results did not allow us to confirm a role for these hormones. Aromatic ITCs generally led to a more severe growth inhibition than the aliphatic allyl-ITC. Interestingly, we observed a correlation between the length of their side chain and the effect these aromatic ITCs caused on Arabidopsis thaliana, with the greatest inhibitory effect seen for 2-phenylethyl-ITC. Root growth recovered when seedlings were removed from exposure to ITCs. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
- Subjects :
- 0106 biological sciences
0301 basic medicine
isothiocyanates
Ethylene
Time Factors
Arabidopsis thaliana
Mutant
Glucosinolates
Arabidopsis
Biology
01 natural sciences
Plant Roots
Catalysis
Article
lcsh:Chemistry
Inorganic Chemistry
growth inhibition
03 medical and health sciences
chemistry.chemical_compound
Structure-Activity Relationship
Auxin
glucosinolates
physiological effects
secondary metabolites
Plant defense against herbivory
Structure–activity relationship
Physical and Theoretical Chemistry
lcsh:QH301-705.5
Molecular Biology
Spectroscopy
chemistry.chemical_classification
Indoleacetic Acids
Organic Chemistry
food and beverages
General Medicine
Ethylenes
biology.organism_classification
Computer Science Applications
030104 developmental biology
lcsh:Biology (General)
lcsh:QD1-999
Biochemistry
chemistry
Seedlings
Glucosinolate
Growth inhibition
010606 plant biology & botany
Subjects
Details
- Language :
- English
- ISSN :
- 14220067
- Database :
- OpenAIRE
- Journal :
- International Journal of Molecular Sciences; Volume 18; Issue 11; Pages: 2372
- Accession number :
- edsair.doi.dedup.....58731bb920c780cdc99d7616f472e0ff
- Full Text :
- https://doi.org/10.3390/ijms18112372