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Genotype-phenotype correlation in cases of juvenile myelomonocytic leukemia with clonal RAS mutations

Authors :
Jan Starý
Henrik Hasle
M. Trebo
Eva Bergsträsser
Franco Locatelli
Christian Flotho
Christian P. Kratz
Dorota Wojcik
Marry M. van den Heuvel-Eibrink
Charlotte M. Niemeyer
Marco Zecca
University of Zurich
Flotho, C
Pediatrics
Source :
Flotho, C, Kratz, C P, Bergsträsser, E, Hasle, H, Stary, J, Trebo, M, van den Heuvel-Eibrink, M M, Wójcik, D, Zecca, M, Locatelli, F, Niemeyer, C M & on behalf of the European Working Group of Myelodysplastic Syndromes in Childhood 2008, ' Genotype-phenotype correlation in cases of juvenile myelomonocytic leukemia with clonal RAS mutations. ', Blood, vol. 111, no. 2, pp. 966-7 . https://doi.org/10.1182/blood-2007-09-111831, Blood, 111(2), 966-967. American Society of Hematology
Publication Year :
2008

Abstract

To the editor: In a recent issue of Blood , Matsuda et al reported 11 children with juvenile myelomonocytic leukemia (JMML) and clonal NRAS or KRAS mutations.[1][1] Three patients showed improvement of various clinical and laboratory features over a 2- to 4-year period without chemotherapy or

Details

Language :
English
ISSN :
00064971
Database :
OpenAIRE
Journal :
Flotho, C, Kratz, C P, Bergsträsser, E, Hasle, H, Stary, J, Trebo, M, van den Heuvel-Eibrink, M M, Wójcik, D, Zecca, M, Locatelli, F, Niemeyer, C M & on behalf of the European Working Group of Myelodysplastic Syndromes in Childhood 2008, ' Genotype-phenotype correlation in cases of juvenile myelomonocytic leukemia with clonal RAS mutations. ', Blood, vol. 111, no. 2, pp. 966-7 . https://doi.org/10.1182/blood-2007-09-111831, Blood, 111(2), 966-967. American Society of Hematology
Accession number :
edsair.doi.dedup.....58669c693f3f0b253939a1b2d79a6ffb
Full Text :
https://doi.org/10.5167/uzh-33768