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Novel variations in the signal peptide region of transforming growth factor beta1 gene in patients with hepatitis: a brief report from India
- Source :
- International Journal of Immunogenetics. 32:79-82
- Publication Year :
- 2005
- Publisher :
- Wiley, 2005.
-
Abstract
- Genotypic status of the signal peptide region of transforming growth factor beta1 (TGF-beta1) showed a significant difference in C/C-genotype frequency at +29 position (codon 10) between a range of viral hepatitis patients and controls (P = 0.009, OR = 3.15, CI = 1.29-7.678), contributed by those who were infected with hepatitis B virus (HBV) alone or HBV + hepatitis delta virus (HDV) (P = 0.003, OR = 5.0, CI = 1.78-13.97).
- Subjects :
- Adult
Male
Signal peptide
viruses
Immunology
Protein Sorting Signals
medicine.disease_cause
Virus
Transforming Growth Factor beta1
Transforming Growth Factor beta
Polymorphism (computer science)
Genotype
Genetics
Humans
Medicine
Codon
Molecular Biology
Genetics (clinical)
Hepatitis B virus
Polymorphism, Genetic
business.industry
Hepatitis A
General Medicine
Middle Aged
Hepatitis B
medicine.disease
Virology
Molecular biology
Hepatitis D
Female
5' Untranslated Regions
business
Viral hepatitis
Transforming growth factor
Subjects
Details
- ISSN :
- 1744313X and 17443121
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- International Journal of Immunogenetics
- Accession number :
- edsair.doi.dedup.....585c284c3f7468b35a3c8878d10c7a9c