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Platelet reactions and immune processes. II. The inhibition of platelet aggregation by complement inhibitors
- Source :
- Thrombosis et diathesis haemorrhagica. 22(3)
- Publication Year :
- 1969
-
Abstract
- SummaryWe have studied the effect of complement inhibitors of various classes on platelet aggregation induced by collagen or by latex. The majority of the complement inhibitors which we studied inhibited collagen- or latex-induced platelet aggregation.The possible role of complement as a mediator in the activation of platelet reactions is discussed.These findings indicate that some chemicals are able to act on some of the immune reactions and also on platelet thrombogenetic reactions. It is suggested that drugs or combination of drugs having such a polyvalence might be of particular benefit in thrombo-immuno-inflammatory conditions.
- Subjects :
- Blood Platelets
Platelet aggregation
Catechols
Silicones
Pharmacology
Immune system
Platelet Adhesiveness
Humans
Lupus Erythematosus, Systemic
Platelet
ortho-Aminobenzoates
Aldehydes
Complement Inactivator Proteins
Chemistry
Cell Membrane
Complement Fixation Tests
Guaiacol
Sodium
Complement Inhibitors
Chloroquine
Hematology
Resorcinols
Sulfinpyrazone
Salicylates
Phenylbutazone
Collagen
Colchicine
Latex Fixation Tests
Subjects
Details
- ISSN :
- 03405338
- Volume :
- 22
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Thrombosis et diathesis haemorrhagica
- Accession number :
- edsair.doi.dedup.....583b820c52707bd92d2457f6a8386541