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Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis
- Source :
- International Journal of Analytical Chemistry, International Journal of Analytical Chemistry, Vol 2019 (2019), Scopus, Repositório Institucional da UNESP, Universidade Estadual Paulista (UNESP), instacron:UNESP
- Publication Year :
- 2019
- Publisher :
- Hindawi Limited, 2019.
-
Abstract
- Made available in DSpace on 2019-10-06T17:00:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-01 An innovative method is validated for the analysis of ertapenem sodium by capillary electrophoresis using potassium phosphate buffer 10 mM pH 7 and 15 kV voltage, in the concentration range of 70 to 120 μg mL-1. Ertapenem had a migration time of 3.15 minutes and the linearity curve was y = 2281.7 x - 24495 with a R2 = 0.9994. Thus, we propose a routine analysis method that meets the principles of green analytical chemistry for the routine analysis of ertapenem sodium by capillary electrophoresis. UNESP-Univ Estadual Paulista Faculdade de Ciências Farmacêuticas KU Leuven-University of Leuven Department of Pharmaceutical and Pharmacological Sciences Pharmaceutical Analysis UNESP-Univ Estadual Paulista Faculdade de Ciências Farmacêuticas
- Subjects :
- Green chemistry
Article Subject
PHARMACEUTICALS
lcsh:Analytical chemistry
VALIDATION
Analytical Chemistry
chemistry.chemical_compound
Capillary electrophoresis
ROBUSTNESS
Potassium phosphate
DRUGS
OPTIMIZATION
Routine analysis
lcsh:QD71-142
Science & Technology
Chromatography
STABILITY
Chemistry, Analytical
Ertapenem sodium
PLACKETT-BURMAN
PERFORMANCE LIQUID-CHROMATOGRAPHY
Chemistry
chemistry
RP-HPLC
Physical Sciences
ACID
Ertapenem
Research Article
Subjects
Details
- ISSN :
- 16878779 and 16878760
- Volume :
- 2019
- Database :
- OpenAIRE
- Journal :
- International Journal of Analytical Chemistry
- Accession number :
- edsair.doi.dedup.....580e7864d81964ec81f66009bbe64433
- Full Text :
- https://doi.org/10.1155/2019/1456313