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Cardiovascular disease in patients with spondyloarthropathies

Authors :
Jean Christophe Cornily
Patrick Godon
Alain Saraux
Florence Arlès
Aurore Brondex
Jacques Mansourati
Gilles Quiniou
Ulric Vinsonneau
Département de Cardiologie (HIA - Cardio)
Hôpital d'Instruction des armées
Optimisation des régulations physiologiques (ORPHY (EA 4324))
Institut Brestois Santé Agro Matière (IBSAM)
Université de Brest (UBO)-Université de Brest (UBO)-Université de Brest (UBO)-Centre Hospitalier Régional Universitaire de Brest (CHRU Brest)
Centre d'Investigation Clinique (CIC - Brest)
Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Immunologie et Pathologie (EA2216)
Université de Brest (UBO)-IFR148
Service de Cardiologie, Brest
Hôpital de la Cavale Blanche - CHRU Brest (CHU - BREST )
Source :
Joint Bone Spine, Joint Bone Spine, Elsevier Masson, 2008, 75 (1), pp.18-21. ⟨10.1016/j.jbspin.2007.04.011⟩
Publication Year :
2008
Publisher :
Elsevier BV, 2008.

Abstract

International audience; Spondyloarthropathies are associated with a greater cardiovascular risk than expected based on the cardiac lesions known to occur in these diseases. The prevalence of several conventional risk factors is high in spondyloarthropathy patients, and chronic inflammation also contributes to premature plaque formation. In addition, susceptibility genes for spondyloarthropathies may be associated with an increased risk of cardiovascular disease. Finally, several drugs used to treat spondyloarthropathies may contribute to the occurrence of cardiovascular events. A careful evaluation of the cardiovascular risk profile is a key component of the management of patients with spondyloarthropathies.

Details

ISSN :
1297319X
Volume :
75
Database :
OpenAIRE
Journal :
Joint Bone Spine
Accession number :
edsair.doi.dedup.....57fed80e32bc0d0d77ce0ce5abd2094c
Full Text :
https://doi.org/10.1016/j.jbspin.2007.04.011