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Additional file 1 of Lactic acid from vaginal microbiota enhances cervicovaginal epithelial barrier integrity by promoting tight junction protein expression
- Publication Year :
- 2022
- Publisher :
- figshare, 2022.
-
Abstract
- Additional file 1: Figure S1. Association between cervicovaginal pH and relative abundance of bacterial L- and D-lactate dehydrogenase [LDH; Log2 intensity based absolute quantification (iBAQ) values]. Figure S2. Multidimensional scaling (MDS) plot of genes differentially expressed by ectocervical epithelial cells treated with 0.3% L-lactic acid (L-LA) pH 3.9 or D-lactic acid (D-LA) pH 3.9 (yellow and blue respectively), HCl pH 3.9 (green) or untreated cells (red). Figure S3. Primary cervicovaginal epithelial cells were apically treated with 0.3% L-lactic acid pH (L-LA, pH 3.9), or low pH media alone (HCl, pH 3.9) for 1 h and gene expression of tight junction factors claudin-1 (CLDN1) and claudin-4 (CLDN4) were assessed 4 h post-treatment by qRT-PCR.
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....57995f3180206f9756ecb2011e168010
- Full Text :
- https://doi.org/10.6084/m9.figshare.20762886