A High-Resolution Genetic Map for the Laboratory Rat

Authors :: Pasi Rastas
John Littrell
Leah Solberg-Woods
Michael J. Flister
Amelie Baud
Shirng-Wern Tsaih
Institute of Biotechnology
University of Helsinki
Source :: G3: Genes, Genomes, Genetics, Vol 8, Iss 7, Pp 2241-2248 (2018), G3: Genes|Genomes|Genetics
Publication Year :: 2018
Publisher :: Oxford University Press, 2018.
Abstract: An accurate and high-resolution genetic map is critical for mapping complex traits, yet the resolution of the current rat genetic map is far lower than human and mouse, and has not been updated since the original Jensen-Seaman map in 2004. For the first time, we have refined the rat genetic map to sub-centimorgan (cM) resolution (