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METHYLATION AND MOOD
- Source :
- The Lancet. 324:196-198
- Publication Year :
- 1984
- Publisher :
- Elsevier BV, 1984.
-
Abstract
- S-adenosylmethionine (SAM) has antidepressant properties. The commonest neuropsychiatric complication of severe folate deficiency is depression. These independent observations suggest that methylation in the nervous system may underlie the expression of mood and related processes and may be implicated in some affective disorders; suggest new biological approaches to the understanding and treatment of some affective disorders; and may explain why methionine sometimes aggravates schizophrenia.
- Subjects :
- Nervous system
S-Adenosylmethionine
medicine.medical_specialty
Anemia, Megaloblastic
Emotions
S-adenosylmethionine metabolism
Folic Acid Deficiency
Bioinformatics
Methylation
chemistry.chemical_compound
Humans
Medicine
Psychiatry
Depression (differential diagnoses)
Depressive Disorder
Methionine
business.industry
Brain
Vitamin B 12 Deficiency
General Medicine
medicine.disease
Vitamin B 12
Mood
medicine.anatomical_structure
chemistry
Schizophrenia
Antidepressant
business
Subjects
Details
- ISSN :
- 01406736
- Volume :
- 324
- Database :
- OpenAIRE
- Journal :
- The Lancet
- Accession number :
- edsair.doi.dedup.....573a3de35bda67afc5a6c49418ee1253
- Full Text :
- https://doi.org/10.1016/s0140-6736(84)90482-3