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Determinants of pregnancy rate in the donor oocyte model: a multivariate analysis of 450 frozen-thawed embryo transfers
- Source :
- Human Reproduction. 24:3082-3089
- Publication Year :
- 2009
- Publisher :
- Oxford University Press (OUP), 2009.
-
Abstract
- BACKGROUND: Conflicting results have been published about the determinants of pregnancy after oocyte donation (OD). We used the OD model to determine predictive factors of pregnancy in the recipient after frozen-thawed embryo transfer (FTET) in a specific series where all the embryos were cryopreserved without any prior selection for fresh transfer. METHODS: We report a retrospective study in a university tertiary care center. Multivariate analysis and logistic regression were used to identify predictive factors of pregnancy in a series of 450 OD FTET cycles in 198 infertile women between January 1992 and December 2006. RESULTS: The mean (± SD) recipient age was 35.7 (± 4.5). Impaired ovarian function was the main indication for OD. The mean ± SD (range) number of embryos transferred was 1.65 ± 0.5 (1-3). Overall clinical pregnancy, implantation and delivery rates were 30, 18 and 23%, respectively. After univariate analysis, pregnancy rates were significantly higher in recipients under 35 years, in women with a body mass index (BMI)
- Subjects :
- Adult
Aging
medicine.medical_specialty
Time Factors
Multivariate analysis
Adolescent
Pregnancy Rate
Statistics as Topic
Gonadotropin-Releasing Hormone
Endometrium
Young Adult
Pregnancy
medicine
Humans
Obesity
Retrospective Studies
Cryopreservation
Gynecology
Univariate analysis
Oocyte Donation
business.industry
Rehabilitation
Obstetrics and Gynecology
Embryo Transfer
medicine.disease
Embryo transfer
Pregnancy rate
Reproductive Medicine
Infertility
Communicable Disease Control
Multivariate Analysis
Gestation
Female
Amenorrhea
France
medicine.symptom
business
Body mass index
Subjects
Details
- ISSN :
- 14602350 and 02681161
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- Human Reproduction
- Accession number :
- edsair.doi.dedup.....572d0a9b5dd31eb940fb5a351b7517f8