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A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study

Authors :
Mikitaka Iguchi
Takao Maekita
Masayuki Kitano
Yuki Kawaji
Yoshiyuki Ida
Hirofumi Yamazaki
Yasunobu Yamashita
Reiko Ashida
Keiichi Hatamaru
Takashi Tamura
Masahiro Itonaga
Takanori Yoshikawa
Source :
Diagnostics, Volume 11, Issue 11, Pages: 2018, Diagnostics, Vol 11, Iss 2018, p 2018 (2021)
Publication Year :
2021
Publisher :
Multidisciplinary Digital Publishing Institute, 2021.

Abstract

Detective flow imaging endoscopic ultrasonography (DFI-EUS) provides a new method to image and detect fine vessels and low-velocity blood flow without using ultrasound contrast agents. The aim of this study was to evaluate the utility of DFI-EUS for pancreatobiliary lesions and lymph nodes. Between January 2019 and January 2020, 53 patients who underwent DFI-EUS, e-FLOW EUS, and contrast-enhanced EUS were enrolled. The ability of DFI-EUS and e-FLOW EUS to detect vessels was compared with that of contrast-enhanced EUS. This article describes the DFI technique along with our first experience of its use for vascular assessment of pancreatobiliary lesions. Vessels were imaged in 34 pancreatic solid lesions, eight intraductal papillary mucinous neoplasms (IPMNs), seven gall bladder lesions, and four swollen lymph nodes. DFI-EUS (91%) was significantly superior to e-FLOW EUS (53%) with respect to detection of vessels (p < 0.001) and for discrimination of mural nodules from mucous clots in IPMN and gallbladder lesions from sludge (p = 0.046). Thus, DFI-EUS has the potential to become an essential tool for diagnosis and vascular assessment of various diseases.

Details

Language :
English
ISSN :
20754418
Database :
OpenAIRE
Journal :
Diagnostics
Accession number :
edsair.doi.dedup.....57173d96616150ba2de4b9bc132b5c86
Full Text :
https://doi.org/10.3390/diagnostics11112018