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Long-term follow-up of an amblyopia treatment study: change in visual acuity 15 years after occlusion therapy
- Source :
- Acta Ophthalmologica, Acta Ophthalmologica, 99(1), E36-E42. Wiley-Blackwell Publishing Ltd
- Publication Year :
- 2021
- Publisher :
- Wiley-Blackwell Publishing Ltd, 2021.
-
Abstract
- Purpose: To determine change in visual acuity (VA) in the population of a previous amblyopia treatment study (Loudon 2006) and assess risk factors for VA decrease. Methods: Subjects treated between 2001 and 2003 were contacted between December 2015 and July 2017. Orthoptic examination was conducted under controlled circumstances and included subjective refraction, best corrected VA, reading acuity, binocular vision, retinal fixation, cover-uncover and alternating cover test. As a measure for degree of amblyopia, InterOcular VA Difference (IOD) at the end of occlusion therapy was compared with IOD at the follow-up examination using Wilcoxon’s signed-rank test. Regression analysis was conducted to determine the influence of clinical and socio-economic factors on changes in IOD. Results: Out of 303 subjects from the original study, 208 were contacted successfully, 59 refused and 15 were excluded because of non-amblyopic cause of visual impairment. Mean IOD at end of therapy (mean age 6.4 years) was 0.11 ± 0.16 logMAR, and IOD at follow-up examination (mean age 18.3 years) was 0.09 ± 0.21 logMAR; this difference was not significant (p = 0.054). Degree of anisometropia (p = 0.008; univariable analysis), increasing anisometropia (p = 0.009; multivariable), eccentric fixation (p
- Subjects :
- 10018 Ophthalmology Clinic
Male
medicine.medical_specialty
Visual acuity
Adolescent
visual acuity
genetic structures
Visual impairment
Population
610 Medicine & health
Amblyopia
03 medical and health sciences
0302 clinical medicine
Ophthalmology
medicine
Humans
Cover test
Prospective Studies
Child
education
Anisometropia
Vision, Binocular
education.field_of_study
business.industry
Original Articles
General Medicine
2731 Ophthalmology
medicine.disease
Subjective refraction
eye diseases
Treatment Outcome
Child, Preschool
long‐term follow‐up
occlusion therapy
Fixation (visual)
Disease Progression
030221 ophthalmology & optometry
Female
Original Article
Sensory Deprivation
medicine.symptom
business
Orthoptic
030217 neurology & neurosurgery
Follow-Up Studies
Forecasting
Subjects
Details
- Language :
- English
- ISSN :
- 17553768 and 1755375X
- Volume :
- 99
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Acta Ophthalmologica
- Accession number :
- edsair.doi.dedup.....570860977bcda4a93872185ac82e9e0b