Back to Search
Start Over
Added value of ovarian reserve testing on patient characteristics in the prediction of ovarian response and ongoing pregnancy: an individual patient data approach
- Source :
- Human Reproduction Update, 19, 26-36, Human Reproduction Update, 19, 1, pp. 26-36, Broer, S L, van Disseldorp, J, Broeze, K A, Dolleman, M, Opmeer, B C, Bossuyt, P, Eijkemans, M J C, Mol, B W J, Broekmans, F J M, Anderson, R A, Ashrafi, M, Bancsi, L, Caroppo, E, Copperman, A, Ebner, T, Geva, M E, Erdem, M, Greenblatt, E M, Jayaprakasan, K, Fenning, R, Klinkert, E R, Kwee, J, Lambalk, C B, La Marca, A, McIlveen, M, Merce, L T, Muttukrishna, S, Nelson, S M, Ng, H Y, Popovic-Todorovic, B, Smeenk, J M J, Tomás, C, Van der Linden, P J Q, van Rooij, I A & Vladimirov, I K 2013, ' Added value of ovarian reserve testing on patient characteristics in the prediction of ovarian response and ongoing pregnancy : An individual patient data approach ', Human Reproduction Update, vol. 19, no. 1, dms041, pp. 26-36 . https://doi.org/10.1093/humupd/dms041, Human Reproduction Update, 19(1):dms041, 26-36. Oxford University Press, Human reproduction update, 19(1), 26-36. Oxford University Press
- Publication Year :
- 2013
-
Abstract
- Item does not contain fulltext BACKGROUND Although ovarian reserve tests (ORTs) are frequently used prior to IVF treatment for outcome prediction, their added predictive value is unclear. We assessed the added value of ORTs to patient characteristics in the prediction of IVF outcome. METHODS An individual patient data (IPD) meta-analysis from published studies was performed. Studies on FSH, anti-Mullerian hormone (AMH) or antral follicle count (AFC) in women undergoing IVF were identified and authors were contacted. Using random intercept logistic regression models, we estimated the added predictive value of ORTs for poor response and ongoing pregnancy after IVF, relative to patient characteristics. RESULTS We were able to collect 28 study databases, comprising 5705 women undergoing IVF. The area under the receiver-operating characteristic curve (AUC) for female age in predicting poor response was 0.61. AFC and AMH each significantly improved the model fit (P-value
- Subjects :
- Anti-Mullerian Hormone
medicine.medical_specialty
Ovarian reserve tests
Individual patient data meta-analysis
Cell Count
Fertilization in Vitro
Logistic regression
Ovarian Follicle
Obstetrics and gynaecology
Predictive Value of Tests
Pregnancy
medicine
AMH
Humans
Ovarian reserve
reproductive and urinary physiology
Gynecology
biology
urogenital system
business.industry
Obstetrics
Ovary
Obstetrics and Gynecology
Anti-Müllerian hormone
Prognosis
Antral follicle
medicine.disease
female genital diseases and pregnancy complications
AFC
ROC Curve
Human Reproduction Renal disorder [NCEBP 12]
Reproductive Medicine
Meta-analysis
Predictive value of tests
IVF outcome prediction
biology.protein
Ovulation Prediction
Female
Follicle Stimulating Hormone
business
therapeutics
hormones, hormone substitutes, and hormone antagonists
Subjects
Details
- Language :
- English
- ISSN :
- 13554786
- Volume :
- 19
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Human reproduction update
- Accession number :
- edsair.doi.dedup.....56ed972acd5a3147ee6f687eacbbc480