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Elevated Plasma Soluble ST2 Is Associated with Heart Failure Symptoms and Outcome in Aortic Stenosis
- Source :
- PLoS ONE, PLoS ONE, Public Library of Science, 2015, 10 (9), pp.e0138940. ⟨10.1371/journal.pone.0138940⟩, PLoS ONE, Vol 10, Iss 9, p e0138940 (2015)
- Publication Year :
- 2015
-
Abstract
- International audience; B-type natriuretic peptide (BNP) is often used as a complementary finding in the diagnostic work-up of patients with aortic stenosis (AS). Whether soluble ST2, a new biomarker of cardiac stretch, is associated with symptomatic status and outcome in asymptomatic AS is unknown. sST2 and BNP levels were measured in 86 patients (74±13 years; 59 asymptomatic, 69%) with AS (23 ng/mL, AUC = 0.68, p
- Subjects :
- Aortic valve
Male
medicine.medical_specialty
medicine.drug_class
lcsh:Medicine
Receptors, Cell Surface
030204 cardiovascular system & hematology
Asymptomatic
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
Natriuretic peptide
Humans
030212 general & internal medicine
lcsh:Science
Aged
Aged, 80 and over
Heart Failure
Multidisciplinary
Ejection fraction
business.industry
lcsh:R
Aortic Valve Stenosis
Middle Aged
medicine.disease
Interleukin-1 Receptor-Like 1 Protein
Stenosis
medicine.anatomical_structure
Aortic valve stenosis
Heart failure
Cardiology
cardiovascular system
Biomarker (medicine)
lcsh:Q
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Female
medicine.symptom
business
Research Article
Subjects
Details
- ISSN :
- 19326203
- Volume :
- 10
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- PloS one
- Accession number :
- edsair.doi.dedup.....56e0086b8c009ff476c1deec773ffb98