Computational Drug Repositioning and Elucidation of Mechanism of Action of Compounds against SARS-CoV-2 - Supplementary data

These are supplementary materials for the paperComputational Drug Repositioning and Elucidation of Mechanism of Action of Compounds against SARS-CoV-2 (preprint available athttps://arxiv.org/abs/2004.07697). Included files: DSEA_screend_drugs.xls Results of Drug Set Enrichment Analysis (http://dsea.tigem.it) on 10 drugs screend against SARS-CoV-2 gene2drug_ACE2TMPRSS2.xls Results of the gene2drug analysis (http://gene2drug.tigem.it) for drugs downregulating ACE2 and TMPRSS2 gene2drug_interactors.xls Results of the gene2drug analysis for drugs down-regulating human SARS-CoV-2 interactors MANTRA_COVID19_Inverse.xlsx Results of the MANTRA analysis (http://mantra.tigem.it)for drugs reverting SARS-CoV-2 induced expression profile PEPs_CMap_msigDB7-covid.zip CMap expression profiles converted to Pathway Expression Profiles using the Gep2pep package (https://bioconductor.org/packages/gep2pep/) and the MSigDB v7 (https://www.gsea-msigdb.org/gsea/msigdb). R data requiringthe gep2pep package.