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Effect of oxytocin during labor on neonatal acidemia
- Source :
- The journal of maternal-fetalneonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 29(19)
- Publication Year :
- 2015
-
Abstract
- Objective: To assess the factors affecting neonatal acidemia, including occurrence of tachysystole/hypertonus in fetuses exposed to oxytocin during labour and with continuously-monitored fetal heart rate (FHR) tracings. Methods: Prospective observational study of all women with term pregnancies who received oxytocin for induction/augmentation of labour. FHR tracings were prospectively classified using ACOG classification. Independent predictors of neonatal acidemia were identified using multivariate linear regression with p < 0.05 considered significant. Results: We included 430 women, 236 of whom (54.9%) had spontaneous onset of labour. The duration of active phase of the second stage of labour and the presence of abnormal FHR tracing during labour were significantly associated with UA pH (p < 0.001) and BE (p < 0.001), while maximum dose of oxytocin (p < 0.17; p < 0.7) and tachysystole (p < 0.9; p < 0.8) were not. At logistic regression, the duration of active phase of the second stage of labour was independently predictive of neonatal acidemia (p < 0.009) while abnormal FHR tracing approached significance (p < 0.088). Conclusions: In women receiving oxytocin during labour, the duration of active phase of the second stage of labour correlates with neonatal acidemia, whereas maximum dose of oxytocin, duration of oxytocin administration and occurrence of tachysystole during labour do not.
- Subjects :
- Pediatrics
medicine.medical_specialty
Time Factors
Cardiotocography
MED/40 - GINECOLOGIA E OSTETRICIA
Logistic regression
Oxytocin
tachysystole
03 medical and health sciences
0302 clinical medicine
Fetus
Labor Stage, Second
Pregnancy
Risk Factors
Bayesian multivariate linear regression
Active phase
Oxytocics
Medicine
neonatal academia
Humans
030212 general & internal medicine
Labor, Induced
Prospective Studies
030219 obstetrics & reproductive medicine
business.industry
Obstetrics
Infant, Newborn
Obstetrics and Gynecology
Heart Rate, Fetal
Obstetric Labor Complications
Fetal heart rate
Logistic Models
Fetal heart rate tracing
Maximum dose
Pediatrics, Perinatology and Child Health
Female
business
Acidosis
medicine.drug
Subjects
Details
- ISSN :
- 14764954
- Volume :
- 29
- Issue :
- 19
- Database :
- OpenAIRE
- Journal :
- The journal of maternal-fetalneonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
- Accession number :
- edsair.doi.dedup.....567628ed43a594f7f117dd4013b0224c