Back to Search
Start Over
[Treatment of Inflammatory Bowel Disease in Elderly Patients - What Are Different and What Should We Know?]
- Source :
- The Korean Journal of Gastroenterology, Vol 77, Iss 5, Pp 231-240 (2021)
- Publication Year :
- 2021
-
Abstract
- As the incidence of inflammatory bowel disease (IBD) are increasing with an ageing population, the incidence and prevalence of IBD in the elderly continue to increase. Older IBD patients can be classified into two groups; elderly-onset IBD patients and elderly IBD patients who were diagnosed at a young age and transitioning into advanced age. Clinicians must consider elderly-onset specific phenotypes or prognosis and age-related concerns in the treatment of elderly IBD patients. There is a paucity of evidence whether there is a different disease process when IBD occurs in older age yet. Clinicians may expect similar therapeutic effects in older and younger patients in drug selection, but since older patients are often excluded from clinical trials, evidence to support this assumption is currently lacking. Also, the risk of side effects may be higher in elderly patients. Therefore, when making management decisions in the elderly, clinicians should assess an individual's frailty rather than only considering an individual's chronological and biological age. Knowing specific requirements for managing older IBD patients may help to make an appropriate therapeutic strategy for this patient group.
- Subjects :
- medicine.medical_specialty
Population ageing
Biological age
Inflammatory bowel disease
03 medical and health sciences
0302 clinical medicine
Older patients
medicine
Prevalence
Humans
Intensive care medicine
Aged
business.industry
Incidence (epidemiology)
Incidence
Therapeutic effect
General Medicine
crohn disease
medicine.disease
Colitis
Inflammatory Bowel Diseases
digestive system diseases
humanities
Clinical trial
Young age
030220 oncology & carcinogenesis
Medicine
030211 gastroenterology & hepatology
Colitis, Ulcerative
business
ulcerative
Subjects
Details
- ISSN :
- 22336869
- Volume :
- 77
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
- Accession number :
- edsair.doi.dedup.....5672154bc6df1226dca5e97dde4178e2