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DNA Extraction Systematics for Spectroscopic Studies

Authors :
Bianca Fogazza Palma
Airton Abrahão Martin
Amanda Borges Ferrari
Renata Andrade Bitar
Herculano da Silva Martinho
Maria Angélica Gargione Cardoso
Source :
Sensors, Vol 8, Iss 6, Pp 3624-3632 (2008), Sensors, Volume 8, Issue 6, Pages: 3624-3632, Sensors (Basel, Switzerland)
Publication Year :
2008
Publisher :
MDPI AG, 2008.

Abstract

Study of genetic material allows the comprehension the origin of the many biochemical changes that follow diseases, like cancer, promoting the development of early preventive inquiry and more efficient individual treatments. Raman spectroscopy can be an important tool in DNA study, since it allows probe molecular vibrations of genetic material in a fast way. The present work established a systematic way for extract DNA in suitable concentrations and structural integrity allowing studies by Raman spectroscopy or other spectroscopic technique, including bio-analytical sensors for probing genetic alterations.

Details

Language :
English
ISSN :
14248220
Volume :
8
Issue :
6
Database :
OpenAIRE
Journal :
Sensors
Accession number :
edsair.doi.dedup.....56496377eee233a24d87efa523744f48