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Méningiomes intracrâniens et utilisation prolongée d’acétate de cyprotérone à dose conventionnelle chez la femme : à propos de deux cas de régression tumorale après arrêt du traitement

Authors :
Jean-Jacques Lemaire
Guillaume Coll
B. Irthum
C. Botella
Service de Neurochirurgie [Clermont-Ferrand]
CHU Clermont-Ferrand-CHU Gabriel Montpied [Clermont-Ferrand]
CHU Clermont-Ferrand
Institut Pascal (IP)
SIGMA Clermont (SIGMA Clermont)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])
Service de Neurochirurgie [CHU Clermont-Ferrand]
CHU Gabriel Montpied [Clermont-Ferrand]
CHU Clermont-Ferrand-CHU Clermont-Ferrand
SIGMA Clermont (SIGMA Clermont)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS)
Source :
Neurochirurgie, Neurochirurgie, Elsevier Masson, 2015, 61 (5), pp.339-342. ⟨10.1016/j.neuchi.2015.05.002⟩, Neurochirurgie, 2015, 61 (5), pp.339-342. ⟨10.1016/j.neuchi.2015.05.002⟩
Publication Year :
2015
Publisher :
HAL CCSD, 2015.

Abstract

The action of synthetic progestogens, prescribed at a conventional dose in women, for a meningioma, is still poorly understood, and could be related to progesterone receptors. We report two cases illustrating multiple meningiomas with stabilization or tumor reduction after withdrawal of cyproterone acetate originally prescribed for a long term period. We also review the influence of synthetic progestogens on meningiomas, particularly the impact of treatment withdrawal.

Details

Language :
French
ISSN :
00283770 and 17730619
Database :
OpenAIRE
Journal :
Neurochirurgie, Neurochirurgie, Elsevier Masson, 2015, 61 (5), pp.339-342. ⟨10.1016/j.neuchi.2015.05.002⟩, Neurochirurgie, 2015, 61 (5), pp.339-342. ⟨10.1016/j.neuchi.2015.05.002⟩
Accession number :
edsair.doi.dedup.....562531c5dda78470229b3dde24b6291a
Full Text :
https://doi.org/10.1016/j.neuchi.2015.05.002⟩