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Colloid milium: a final degeneration product of actinic elastoid
- Source :
- Journal of cutaneous pathology. 12(2)
- Publication Year :
- 1985
-
Abstract
- Serum amyloid P component (SAP) is present not only in all types of cutaneous amyloidosis, but also in the normal dermal elastic fibers as well as abnormal elastic fibers, such as elastotic degeneration of elastic fibers in actinic keratosis. It was previously postulated that the colloid substance in colloid milium is a final degeneration stage of actinic elastosis. In a lesion of colloid milium SAP was intensely positive with an indirect immunofluorescence method using rabbit antiserum to human SAP. Electron microscopy of the colloid lesion revealed components of normal elastic fibers as well as those of actinic elastoid as seen in actinic elastosis. It is concluded that the colloid substance derives, at least in major part, from elastic fibers through actinic degeneration.
- Subjects :
- Male
endocrine system
Pathology
medicine.medical_specialty
Amyloid
Histology
Biopsy
Fluorescent Antibody Technique
Dermatology
Degeneration (medical)
complex mixtures
Skin Diseases
Pathology and Forensic Medicine
Lesion
Colloid
medicine
Humans
Colloids
Aged
Skin
Chemistry
digestive, oral, and skin physiology
Actinic keratosis
Actinic elastosis
medicine.disease
Elastic Tissue
Microscopy, Electron
Serum Amyloid P-Component
Solar keratosis
medicine.anatomical_structure
Sunlight
Keratins
medicine.symptom
Amyloid (mycology)
Elastic fiber
Subjects
Details
- ISSN :
- 03036987
- Volume :
- 12
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of cutaneous pathology
- Accession number :
- edsair.doi.dedup.....5610054fdd6fc557f4586ab8172c117a