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Office and Ambulatory Arterial Hypertension in Highlanders
- Source :
- Hypertension. 76:1962-1970
- Publication Year :
- 2020
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2020.
-
Abstract
- Millions of people worldwide live at high altitude, being chronically exposed to hypobaric hypoxia. Hypertension is a major cardiovascular risk factor but data on its prevalence and determinants in highlanders are limited, and systematic studies with ambulatory blood pressure monitoring are not available. Aim of this study was to assess the prevalence of clinic and ambulatory hypertension and the associated factors in a sample of Andean highlanders. Hypertension prevalence and phenotypes were assessed with office and ambulatory blood pressure measurement in a sample of adults living in Cerro de Pasco, Peru (altitude 4340 m). Basic clinical data, blood oxygen saturation, hematocrit, and Qinghai Chronic Mountain Sickness score were obtained. Participants were classified according to the presence of excessive erythrocytosis and chronic mountain sickness diagnosis. Data of 289 participants (143 women, 146 men, mean age 38.3 years) were analyzed. Office hypertension was present in 20 (7%) participants, while ambulatory hypertension was found in 58 (20%) participants. Masked hypertension was common (15%), and white coat hypertension was rare (2%). Among participants with ambulatory hypertension, the most prevalent phenotypes included isolated nocturnal hypertension, isolated diastolic hypertension, and systodiastolic hypertension. Ambulatory hypertension was associated with male gender, age, overweight/obesity, 24-hour heart rate, and excessive erythrocytosis. Prevalence of hypertension among Andean highlanders may be significantly underestimated when based on conventional blood pressure measurements, due to the high prevalence of masked hypertension. In highlanders, ambulatory hypertension may be independently associated with excessive erythrocytosis.
- Subjects :
- Adult
Male
medicine.medical_specialty
hypertension
Ambulatory blood pressure
Office Visits
hematocrit
Blood viscosity
Diastolic Hypertension
White coat hypertension
Altitude Sickness
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
Masked Hypertension
Internal medicine
Peru
Prevalence
Internal Medicine
Humans
Medicine
030212 general & internal medicine
Hypoxia
business.industry
Altitude
Blood Pressure Monitoring, Ambulatory
Middle Aged
medicine.disease
ambulatory blood pressure monitoring
Cross-Sectional Studies
Blood pressure
Chronic mountain sickness
polycythemia
Ambulatory
blood viscosity
Female
business
Subjects
Details
- ISSN :
- 15244563 and 0194911X
- Volume :
- 76
- Database :
- OpenAIRE
- Journal :
- Hypertension
- Accession number :
- edsair.doi.dedup.....55bfd4a9013028bd25859fe7b7accf0a