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Relation Between V˙E/V˙CO2 Slope and Maximum Phonation Time in Chronic Heart Failure Patients
- Source :
- Medicine
- Publication Year :
- 2014
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2014.
-
Abstract
- This study aimed to determine the relation between the regression slope relating minute ventilation to carbon dioxide output (V˙E/V˙CO2 slope) and maximum phonation time (MPT), and the MPT required to attain a threshold value for V˙E/V˙CO2 slope of ≤34 in chronic heart failure (CHF) patients. This cross-sectional study enrolled 115 CHF patients (mean age, 54.5 years; men, 84.9%). V˙E/V˙CO2 slope was assessed during cardiopulmonary exercise testing (CPX). Thereafter, patients were divided into 2 groups according to exercise capacity: V˙E/V˙CO2 slope ≤34 (V˙E/V˙CO2 ≤34 group, n = 81) and V˙E/V˙CO2 slope >34 (V˙E/V˙CO2 >34 group, n = 34). For MPT measurements, all patients produced a sustained vowel/a:/ for as long as possible during respiratory effort from the seated position. All subjects showed significant negative correlation between V˙E/V˙CO2 slope and MPT (r = −0.51, P 34 group (21.4 ± 6.4 vs 17.4 ± 4.3 s, F = 7.4, P = 0.007). The appropriate MPT cut-off value for identifying a V˙E/V˙CO2 slope ≤34 was 18.12 seconds. An MPT value of 18.12 seconds may be a useful target value for identifying CHF patients with a V˙E/V˙CO2 slope ≤34 and for risk management in these patients.
- Subjects :
- Male
medicine.medical_specialty
Observational Study
Significant negative correlation
Article
Phonation
Internal medicine
medicine
Humans
Respiratory effort
Carbon dioxide output
Heart Failure
Exercise Tolerance
Pulmonary Gas Exchange
business.industry
Maximum phonation time
General Medicine
Middle Aged
Exercise capacity
medicine.disease
Ve vco2 slope
Surgery
Cross-Sectional Studies
Heart failure
Cardiology
Female
Erratum
Pulmonary Ventilation
business
human activities
Respiratory minute volume
circulatory and respiratory physiology
Subjects
Details
- ISSN :
- 00257974
- Volume :
- 93
- Database :
- OpenAIRE
- Journal :
- Medicine
- Accession number :
- edsair.doi.dedup.....55ac6a3b72b9b54e482e7a4765d3c9b8
- Full Text :
- https://doi.org/10.1097/md.0000000000000306