CRT-500.10 Ridaforolimus Eluting Stents with Customizable Diffusion Controlled Release Kinetics and Tissue Uptake

Drug release from spray coatings applied to cylindrical stents is difficult to customize due to intermixing of successively coated layers. Flat sheets of electropolished L-605 Cobalt Chromium alloy were spray coated with a solution of Ridaforolimus and two polymers, folded and welded into cylinders