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The safety and short-term efficacy of a novel polyurethane meniscal scaffold for the treatment of segmental medial meniscus deficiency
- Source :
- Knee Surgery, Sports Traumatology, Arthroscopy. 20:1822-1830
- Publication Year :
- 2011
- Publisher :
- Springer Science and Business Media LLC, 2011.
-
Abstract
- Meniscal loss is associated with an increased risk of developing osteoarthritis. Tissue engineering solutions, which include the development of novel material scaffolds, are being utilised to aid the regeneration of meniscal tissue. The purpose of this study was to monitor the safety profile and the short-term efficacy of a novel polyurethane meniscal scaffold in the treatment of patients with painful knees following partial medial meniscectomy. Ten consecutive patients with segmental tissue loss from the medial meniscus were treated with the arthroscopic implantation of an Actifit® (Orteq Sports Medicine) polyurethane meniscal scaffold. Patients were followed up at 2 and 6 weeks, then again at 6 and 12 months. Primary outcome measures included reporting of complications and patient-reported outcome scores (KOOS, KSS, UCLA Activity scale, VAS pain). Secondary outcome was MRI assessment at 6 and 12 months looking at scaffold morphology, integration and associated joint injury/inflammation. Eight male and 2 female patients were included in the study with a mean age of 29 (range 18–45). No complications were reported. All patients were happy with their surgery. At 6 months, a statistically significant improvement (P
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Knee Joint
Sports medicine
Visual analogue scale
Polyurethanes
Biocompatible Materials
Osteoarthritis
Menisci, Tibial
Arthroscopy
Young Adult
medicine
Humans
Orthopedics and Sports Medicine
Tissue Scaffolds
medicine.diagnostic_test
business.industry
Prostheses and Implants
Middle Aged
medicine.disease
Tibial Meniscus Injuries
Surgery
Treatment Outcome
medicine.anatomical_structure
Orthopedic surgery
Female
Implant
Joint Diseases
business
Cartilage Diseases
Medial meniscus
Subjects
Details
- ISSN :
- 14337347 and 09422056
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Knee Surgery, Sports Traumatology, Arthroscopy
- Accession number :
- edsair.doi.dedup.....55904c74ecad8ac0c77133fc16d3ce9d