Administration of glycerol-based formulations in sheep results in similar ovulation rate to eCG but red blood cell indices may be affected

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The objective of this study was to investigate the metabolic and osmotic effects of different doses of glycerol or a glycerol - propylene glycol mixture in Sarda sheep with the aim to identify those able to beneficially modify ewe's metabolic status without harmful changes in red blood cell (RBC) indices. Thereafter, the selected doses were tested for their effects on ewe's ovarian activity during an induced follicular phase and compared to the effects of a hormonal treatment with equine chorionic gonadotrophin (eCG).
This study was financed by a doctoral grant from the Italian Ministry of Education, University and Research (Programma Operativo Nazionale Ricerca e Innovazione 2014–2020 - CCI 2014IT16M2OP005 - Fondo Sociale Europeo, Azione I.1 “Dottorati Innovativi con caratterizzazione Industriale). The funding institution financed laboratory analysis, the dietary treatments, and FDS. The funding institution had no role in the design of the study; in the collection, analysis, and interpretation of data; or in the writing of the manuscript.