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Citrus polymethoxylated flavones improve lipid and glucose homeostasis and modulate adipocytokines in fructose-induced insulin resistant hamsters
- Source :
- Life Sciences. 79:365-373
- Publication Year :
- 2006
- Publisher :
- Elsevier BV, 2006.
-
Abstract
- The present study was undertaken to determine whether supplementation with polymethoxylated flavones (PMFs) could ameliorate the fructose-induced hypertriglyceridemia and other metabolic abnormalities associated with insulin resistance (IR) in hamsters. Following feeding with the fructose diet, hamsters were supplemented orally with PMF-L or PMF-H (62.5 and 125 mg/kg/day) for 4 weeks. Both PMF-treated groups showed a statistically significant (p
- Subjects :
- Blood Glucose
Male
Citrus
medicine.medical_specialty
medicine.medical_treatment
Hypercholesterolemia
Administration, Oral
Fructose
Biology
General Biochemistry, Genetics and Molecular Biology
chemistry.chemical_compound
Insulin resistance
Cricetinae
Internal medicine
Adipocytes
medicine
Animals
Homeostasis
Glucose homeostasis
General Pharmacology, Toxicology and Pharmaceutics
Triglycerides
Hypolipidemic Agents
Glucose tolerance test
Mesocricetus
Triglyceride
Adiponectin
medicine.diagnostic_test
Plant Extracts
Insulin
Hypertriglyceridemia
General Medicine
Glucose Tolerance Test
Flavones
medicine.disease
Lipids
PPAR gamma
Disease Models, Animal
Cholesterol
Endocrinology
Liver
chemistry
Cytokines
Insulin Resistance
Subjects
Details
- ISSN :
- 00243205
- Volume :
- 79
- Database :
- OpenAIRE
- Journal :
- Life Sciences
- Accession number :
- edsair.doi.dedup.....55535e6450bf38dc4cfd7f8534e5de66