Back to Search
Start Over
Configuration analysis of the injection position and shape of the gel spacer in gynecologic brachytherapy
- Source :
- Brachytherapy. 20:95-103
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Purpose In this single-institution retrospective study, configuration analysis was performed to determine the optimal location and volume of hyaluronic acid gel spacer injection into the rectovaginal or vesicovaginal septum for effective dose reduction (DR) to the organs at risk (OARs), the rectum and bladder. Methods and materials 70 and 50 intracavitary brachytherapy treatment plans used only vaginal cylinders with gel spacers for the rectal and bladder sides, respectively, whereas 28 did not use spacers. Correlation analysis was performed between the geometrical parameters and injection position of the gel spacers and the 2-cm3 covering doses of the OARs for each treatment. Results A higher DR was predicted for hyaluronic acid gel spacer injection within ±5 mm and ±2.5 mm in the lateral-medial direction from the midpoint on the rectal and bladder sides, and ±10 mm in the cranial–caudal direction from the midpoint on the rectal side. There were correlations between 2-cm3 covering doses and the gel spacer parameters: the volume on the rectal (p = 0.02) and bladder (p = 0.04) sides; the craniocaudal length on the rectal side (p > 0.05). Conclusions A gel spacer volume of ∼10 cm3 provides sufficient OAR DR if its gravity point is on the midpoint between the cylinder applicator and OAR, and its craniocaudal length covers the active length of the cylinder applicator.
- Subjects :
- Organs at Risk
medicine.medical_treatment
Brachytherapy
Uterine Cervical Neoplasms
Rectum
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Radiology, Nuclear Medicine and imaging
Gynecologic brachytherapy
Retrospective Studies
business.industry
Radiotherapy Planning, Computer-Assisted
Intracavitary brachytherapy
Vesicovaginal septum
Radiotherapy Dosage
Configuration analysis
medicine.anatomical_structure
Oncology
030220 oncology & carcinogenesis
Correlation analysis
Female
Nuclear medicine
business
Subjects
Details
- ISSN :
- 15384721
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Brachytherapy
- Accession number :
- edsair.doi.dedup.....553ded898d1f31bcf8596392c73c9519