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HPLC-DAD-MS identification of bioactive secondary metabolites from Ferula communis roots
- Source :
- Fitoterapia. 75:342-354
- Publication Year :
- 2004
- Publisher :
- Elsevier BV, 2004.
-
Abstract
- A simple HPLC method was developed to distinguish between 'poisonous' and 'non-poisonous' chemotypes of Ferula communis. The method was performed on a C8 reverse phase analytical column using a binary eluent (aqueous TFA 0.01%-TFA 0.01% in acetonitrile) under gradient condition. The two chemotypes showed different fingerprints. The identification of five coumarins and eleven daucane derivatives by HPLC-diode array detection (HPLC-DAD) and HPLC-MS is described. A coumarin, not yet described, was detected.
- Subjects :
- Metabolite
Protein Prenylation
Pharmacognosy
Plant Roots
High-performance liquid chromatography
Mass Spectrometry
chemistry.chemical_compound
Column chromatography
Coumarins
Drug Discovery
Humans
Ferula communis
Chromatography, High Pressure Liquid
Pharmacology
Chromatography
biology
Chemotype
Plant Extracts
Reproducibility of Results
General Medicine
biology.organism_classification
Coumarin
Ferula
chemistry
Protein prenylation
Phytotherapy
Subjects
Details
- ISSN :
- 0367326X
- Volume :
- 75
- Database :
- OpenAIRE
- Journal :
- Fitoterapia
- Accession number :
- edsair.doi.dedup.....54f43795b8f99a612c2748b50b90f36d