Detection of Maternal DNA in Umbilical Cord Plasma by Fluorescent PCR Amplification of Short Tandem Repeat Sequences

Authors :: Margit Bauer
Wolfgang Schoell
Barbara Pertl
Diana W. Bianchi
Irmgard Orescovic
Source :: Annals of the New York Academy of Sciences. 945:161-163
Publication Year :: 2006
Publisher :: Wiley, 2006.
Abstract: Recently, maternal DNA was detected in umbilical cord blood using PCR amplification of minisatellite sequences. The presence of maternal DNA was demonstrated in 1% to 100% of umbilical cord blood samples. The objective of this study was to determine the frequency of cord blood contamination by maternal genetic material. We used fluorescent PCR amplification of highly polymorphic short tandem repeat (STR) markers to detect maternal DNA in umbilical cord plasma.

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