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Black chokeberry Aronia melanocarpa extract reduces blood pressure, glycemia and lipid profile in patients with metabolic syndrome: a prospective controlled trial
- Source :
- Molecular and Cellular Biochemistry. 476:2663-2673
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- The aim of the study was to examine the effect of 4-week supplementation of Alixir 400 PROTECT® (Standardized Aronia L. Melanocarpa Extract Extract-SAE) on clinical and biochemical parameters in patients with confirmed metabolic syndrome (MetS). This study was designed as a prospective open-label clinical case-series study with 28 days of follow-up with cases selected and followed during the period from February 1, 2018 to November 2019. The study included 143 male and female patients with MetS who were subjected to SAE. SAE supplementation significantly altered SP, BP as well as HR values. After 2 weeks, CHOL levels significantly decreased in the fMetS-DM group compared to the baseline values in this group, while the LDL levels significantly decreased in the fMetS group. Triglycerides significantly decreased only after 4 weeks of SAE treatment in diabetic groups of patients (fMetS-DM and mMetS-DM) compared to the baseline, while in non-diabetic groups this marker was not significantly altered. Increased polyphenols or SAE consumption is correlated with a positive effect on body weight, total cholesterol, low and high-density lipoproteins, blood pressure and glycemia. Increasing consumption of polyphenol-rich foods could be a promising strategy to reduce cardiovascular risk.
- Subjects :
- Adult
Blood Glucose
Male
0301 basic medicine
medicine.medical_specialty
Clinical chemistry
Clinical Biochemistry
Blood Pressure
Gastroenterology
law.invention
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
law
Internal medicine
Photinia
parasitic diseases
medicine
Humans
In patient
Prospective Studies
Molecular Biology
Aged
Metabolic Syndrome
medicine.diagnostic_test
Plant Extracts
business.industry
Cell Biology
General Medicine
Middle Aged
medicine.disease
Lipids
030104 developmental biology
Blood pressure
030220 oncology & carcinogenesis
Aronia melanocarpa
Female
Aronia
Metabolic syndrome
Lipid profile
business
Subjects
Details
- ISSN :
- 15734919 and 03008177
- Volume :
- 476
- Database :
- OpenAIRE
- Journal :
- Molecular and Cellular Biochemistry
- Accession number :
- edsair.doi.dedup.....54b823f4153dcbbd15d9d67713f9bf6a