Additional file 2 of Clinical, molecular and glycophenotype insights in SLC39A8-CDG

Additional file 2. Fig. S2. MALDI-TOF mass spectra of permethylated transferrin N-glycans in SLC39A8-CDG Patient-3 compared to a reference control. Transferrin N-glycan analysis in a pediatric representative control (a). Transferrin N-glycosylation analysis of Patient-3 (b), showing very slight unspecific glycosylation changes with minor increases of hyposialylated and fucosylated glycoforms. Compared to control, the observed changes are outlined by red marks. Glycan structures were assigned following consortium for functional glycomics guidelines: N-acetylglucosamine, blue square; mannose, green circle; galactose, yellow circle; sialic acid, purple lozenge; fucose, red triangle.