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Transcriptome-wide and differential expression network analyses of childhood asthma in nasal epithelium

Authors :
Daniel E. Weeks
Glorisa Canino
Nadia Boutaoui
Edna Acosta-Pérez
Zhao Ren
Wei Chen
Yueh-Ying Han
Soyeon Kim
Juan C. Celedón
Yale Jiang
Rong Zhang
Franziska Rosser
Qi Yan
Angel Colón-Semidey
María Alvarez
Erick Forno
Source :
J Allergy Clin Immunol
Publication Year :
2020
Publisher :
Elsevier BV, 2020.

Abstract

In a transcription-wide association study of nasal epithelium, we identify novel and previously reported susceptibility genes for atopic asthma in children and show that gene co-expression networks differ markedly between children with and without atopic asthma.

Details

ISSN :
00916749
Volume :
146
Database :
OpenAIRE
Journal :
Journal of Allergy and Clinical Immunology
Accession number :
edsair.doi.dedup.....5444c17870de3995635fbefdb163cad6