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Detection, treatment and outcome of axillary recurrence after axillary clearance for invasive breast cancer
- Source :
- The British journal of surgery. 88(1)
- Publication Year :
- 2001
-
Abstract
- Background The aim was to gain insight into the diagnosis, treatment and prognosis of axillary recurrence after axillary clearance for invasive breast cancer in a large patient series. Methods Between 1984 and 1994, 4669 patients with invasive breast cancer underwent axillary clearance in eight community hospitals in the south-eastern part of the Netherlands. Using follow-up data in a population-based cancer registry, 59 patients with axillary recurrence were identified. Results The median interval between treatment of the primary tumour and the diagnosis of axillary recurrence was 2·6 (range 0·3–10·7) years. In 51 patients (86 per cent), axillary recurrence was found by palpation during routine follow-up. Surgery was part of the treatment of recurrence for 41 of 59 patients. Regional control (complete eradication of axillary recurrence) was achieved in 34 patients (58 per cent). The 5-year actuarial survival rate was 39 (95 per cent confidence interval 25–53) per cent. Patients with negative axillary lymph nodes at the time of diagnosis of the primary tumour and complete eradication of axillary recurrence had the best prognosis. Conclusion Patients with axillary recurrence had a poor prognosis, except when complete eradication was achieved and axillary lymph nodes were negative at the time of diagnosis of the primary tumour.
- Subjects :
- Adult
medicine.medical_specialty
Axillary lymph nodes
Population
Breast Neoplasms
Palpation
Breast cancer
medicine
Humans
Neoplasm Invasiveness
education
Survival analysis
Aged
Aged, 80 and over
education.field_of_study
Analysis of Variance
medicine.diagnostic_test
business.industry
Middle Aged
medicine.disease
Survival Analysis
Surgery
Cancer registry
Axilla
medicine.anatomical_structure
Treatment Outcome
Lymphatic Metastasis
Lymph Node Excision
Female
business
Complication
Follow-Up Studies
Subjects
Details
- ISSN :
- 00071323
- Volume :
- 88
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- The British journal of surgery
- Accession number :
- edsair.doi.dedup.....53b217886dc57dc03691b07320361d96