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Multi-panel, on-single-chip Memristive Biosensing
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Abstract
- Memristive biosensors have demonstrated excellent capabilities for ultrasensitive bio-detection. In the present work, memristive biosensing chips are designed, fabricated and implemented in a for the first time presented multi-panel on-chip detection for discrete sensing of a target molecule through separate functionalization of individual devices on the same chip. The biosensing scheme is validated by means of labeled (i.e. fluorescence) and label-free (i.e. electrical) characterization methods. This novel memristive multi-panel sensing paradigm paves the way for fast and ultrasensitive PoC (point-of-care) devices allowing the detection of specific targets in complex matrixes where non-specific molecules are present as well, and opening great potential for the application of memristive phenomena in multiplexed ultrasensitive bio-detection and theranostics.
- Subjects :
- Single chip
Materials science
Monitoring
Nanowires
010401 analytical chemistry
Nanowire
Nanotechnology
Chip
01 natural sciences
Multiplexing
Fluorescence
0104 chemical sciences
Biosensors
Nanoscale devices
Biomarkers
Characterization methods
Nanowires Monitoring
Electrical and Electronic Engineering
Instrumentation
Biosensor
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....53af2a5029e2782b5a19b90e5b79a7ba