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Path finding approaches and metabolic pathways
- Source :
- Discrete Applied Mathematics. (10):2244-2256
- Publisher :
- Elsevier B.V.
-
Abstract
- A metabolic pathway is a set of enzyme catalysed biochemical reactions by which a living organism transforms an initial (source) compound into a final (target) compound. Path finding approaches to metabolic pathways adopt a graph theory approach to the problem of determining the reactions an organism might use to transform a source compound into a target compound. In this paper, the effectiveness of using compound node connectivities in a path finding approach is examined. An approach to path finding based upon integer programming is also presented.
Details
- Language :
- English
- ISSN :
- 0166218X
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Discrete Applied Mathematics
- Accession number :
- edsair.doi.dedup.....539ff2b1c244e19e8bc279135c8cfd9a
- Full Text :
- https://doi.org/10.1016/j.dam.2008.06.035