Back to Search Start Over

GENOTOXICITY ASSESSMENT OF IRON OXIDE NANOPARTICLES IN MALE WISTAR RATS AFTER CHRONIC ORAL TREATMENT

Authors :
Nevenka Kopjar
Vedran Micek
Marin Mladinić
Vilena Kašuba
Davor Zeljezic
Ruzica Rozgaj
Kehrer JP, Dekant W, Li Y, Smith CV, Panagiotidis MI, Menzel DB.
Publication Year :
2014

Abstract

The use of iron oxide nanoparticles (Fe2O3 np) in medical diagnostics and therapy is growing in recent years. Concern about the possible adverse effects on living organisms and the environment has prompted research on its toxicity and genotoxicity. The aim of this study was to investigate the possible genotoxic effects of chronic exposure of rats to Fe2O3 np. Twenty-five albino male Wistar rats aged 10 weeks were divided into groups of five animals. Three groups were orally treated with Fe2O3 np (

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....53988c0a407800de463785982d4cdd2c