Back to Search
Start Over
Intra-Abdominal Pressure as a Marker of Enteral Nutrition Intolerance in Critically Ill Patients. The PIANE Study
- Source :
- Nutrients, Vol 11, Iss 11, p 2616 (2019), Dipòsit Digital de Documents de la UAB, Universitat Autònoma de Barcelona, Nutrients, Volume 11, Issue 11, r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA, instname, r-FISABIO: Repositorio Institucional de Producción Científica, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
- Publication Year :
- 2019
- Publisher :
- MDPI AG, 2019.
-
Abstract
- To determine whether elevated intra-abdominal pressure (IAP) is associated with a higher rate of enteral nutrition-related gastrointestinal (GI) complications<br />to assess the value of IAP as a predictor of enteral nutrition (EN) intolerance. Intensive Care Unit (ICU) patients on mechanical ventilation requiring at least 5 days of EN were recruited for a prospective, observational, non-interventional, multicenter study. EN was performed and GI complications were managed with an established protocol. IAP was determined via a urinary catheter. Patients who developed any GI complications were considered as presenting EN intolerance. Variables related to EN, IAP and GI complications were monitored daily. Statistical analysis compared patients without GI complications (group A) vs. GI complications (group B). 247 patients were recruited from 28 participating ICUs (group A: 119, group B: 128). No differences between groups were recorded. Patients in group B (p &lt<br />0.001) spent more days on EN (8.1 ± 8.4 vs. 18.1 ± 13.7), on mechanical ventilation (8.0 ± 7.7 vs. 19.3 ± 14.9) and in the ICU (12.3 ± 11.4 vs. 24.8 ± 17.5). IAP prior to the GI complication was (14.3 ± 3.1 vs. 15.8 ± 4.8) (p &lt<br />0.003). The best IAP value identified for EN intolerance was 14 mmHg but it had low sensitivity and specificity. Although a higher IAP was associated with EN intolerance, IAP alone did not emerge as a good predictor of EN intolerance in critically ill patients.
- Subjects :
- Male
Gastrointestinal Diseases - etiology
Gastrointestinal Diseases
medicine.medical_treatment
humanos
asistencia del enfermo crítico
intensive care unit
Gastroenterology
Enteral administration
Group B
law.invention
0302 clinical medicine
law
estudios prospectivos
Abdomen
Prospective Studies
030212 general & internal medicine
Prospective cohort study
mediana edad
anciano
Nutrition and Dietetics
Respiration
enfermedades gastrointestinales
respiración
gastrointestinal complications
Middle Aged
Intensive care unit
Intensive Care Units
presión
medicine.anatomical_structure
intra-abdominal pressure
Female
lcsh:Nutrition. Foods and food supply
medicine.medical_specialty
Critical Care
Critical Illness
unidades de cuidados intensivos
enfermedad crítica
lcsh:TX341-641
Article
enteral nutrition intolerance
03 medical and health sciences
Internal medicine
Pressure
medicine
Humans
enteral nutrition
nutrición enteral
Aged
Mechanical ventilation
business.industry
030208 emergency & critical care medicine
Respiration, Artificial
Critical Illness - therapy
Parenteral nutrition
business
Complication
Biomarkers
Food Science
Subjects
Details
- ISSN :
- 20726643
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- Nutrients
- Accession number :
- edsair.doi.dedup.....53552fe90368a9f0296403318918cacb