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INHIBITION OF DAPSONE EXCRETION BY PROBENECID
- Source :
- The Lancet. 294:884-885
- Publication Year :
- 1969
- Publisher :
- Elsevier BV, 1969.
-
Abstract
- In 12 Ethiopian men probenecid given with dapsone caused a significant reduction in urinary excretion of acid-labile dapsone metabolites, and to a lesser extent free dapsone, and also raised the blood-levels of dapsone. The method of estimating serum-levels of dapsone by Schiff-base formation was modified for use with urine.
Details
- ISSN :
- 01406736
- Volume :
- 294
- Database :
- OpenAIRE
- Journal :
- The Lancet
- Accession number :
- edsair.doi.dedup.....5341191f38a69d7933666faf802795d3
- Full Text :
- https://doi.org/10.1016/s0140-6736(69)92334-4