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Rubella Seropositivity in Pregnant Women After Vaccination Campaign in Brazil's Federal District

Authors :
Lenora Gandolfi
Franco Batista Leite
Tamires Vital
Inês Sequeira
Elsa Moreira
Nadjar Nitz
Yanna Karla de Medeiros Nóbrega
Riccardo Pratesi
Mariana Hecht
Bruna de Carvalho
Juliana K.B. de Andrade
Source :
Viral Immunology. 30:675-677
Publication Year :
2017
Publisher :
Mary Ann Liebert Inc, 2017.

Abstract

Rubella is an acute viral disease that usually does not generate sequels; however, in pregnant women the infection can cause serious abnormalities to fetuses, which are collectively called congenital rubella syndrome. In Brazil, population immunization was started in 1992, but few epidemiological studies have been conducted to assess vaccination coverage and seroconversion since then. The aim of this work is to evaluate the seropositivity of pregnant women to rubella virus after vaccination campaign was carried out in 2008. Serological tests for rubella diagnosis were performed in 87 pregnant women who attended the University of Brasilia Hospital, Federal District, Brazil. Antirubella IgG antibodies were detected in 83 out of 87 pregnant women (95.4%), with an age-independent seroprevalence. Only one woman was positive in IgM serological tests. Our data suggest high levels of vaccination coverage and antirubella immunization in the Brazil Federal District population.

Details

ISSN :
15578976 and 08828245
Volume :
30
Database :
OpenAIRE
Journal :
Viral Immunology
Accession number :
edsair.doi.dedup.....5300a8f12285bba5a828d506586f9536
Full Text :
https://doi.org/10.1089/vim.2017.0012